Reno 911! Chronicled the group of officers attending a police convention in Maimi, Fl. Upon reaching the convention center and attempting to gain entrance, their passes are denied, as the Reno sheriffs department is not on the guest list. While the team is waiting outside, a biological agent of unknown origin is released inside the convention center, causing all the police officers in Miami, and many from around the country, to be quarantined until the biological agent can be identified and an antidote can be found. Lieutenant Jim Dangle (Thomas Lennon) quickly takes charge of the situation and mans the massive police station. The team get into various hijinks across Miami, led by Dangle and the Mayor’s assistant Jeff Spoder (Patton Oswalt), who is trying vainly to keep the Reno team and the city under control. As the team runs afoul a major Miami drug lord with ties to the biological agent in the convention center, they begin to get an idea just how crazy people can get in Florida.